D-arabinitol 4-dehydrogenase explained

D-arabitol 4-dehydrogenase
Ec Number:	1.1.1.11
Cas Number:	9028-18-6
Go Code:	0047813

In enzymology, a D-arabinitol 4-dehydrogenase is an enzyme that catalyzes the chemical reaction

D-arabinitol + NAD⁺

\rightleftharpoons D-xylulose + NADH + H⁺

Thus, the two substrates of this enzyme are D-arabinitol and NAD⁺, whereas its 3 products are D-xylulose, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is D-arabinitol:NAD⁺ 4-oxidoreductase. Other names in common use include D-arabitol dehydrogenase and arabitol dehydrogenase. This enzyme participates in pentose and glucuronate interconversions and fructose and mannose metabolism.

References

• Characterization of Arabitol Dehyrogenase in Transplastomic Plants. LAP Lambert Academic Publishing.
• Lin ECC . 1961 . An inducible D-arabitol dehydrogenase from Aerobacter aerogenes . J. Biol. Chem. . 236 . 31 - 36 . 13762204.
• Wood WA, McDonough MJ, Jacobs LB . 1961 . Ribitol and D-arabitol utilization by Aerobacter aerogenes . J. Biol. Chem. . 236 . 2190 - 2195 .