| D-alanine 2-hydroxymethyltransferase | |
| Ec Number: | 2.1.2.7 |
| Cas Number: | 9075-76-7 |
| Go Code: | 0050413 |
In enzymology, a D-alanine 2-hydroxymethyltransferase is an enzyme that catalyzes the chemical reaction
5,10-methylenetetrahydrofolate + D-alanine + H2O
\rightleftharpoons
The 3 substrates of this enzyme are 5,10-methylenetetrahydrofolate, D-alanine, and H2O, whereas its two products are tetrahydrofolate and 2-methylserine.
This enzyme belongs to the family of transferases that transfer one-carbon groups, specifically the hydroxymethyl-, formyl- and related transferases. The systematic name of this enzyme class is 5,10-methylenetetrahydrofolate:D-alanine 2-hydroxymethyltransferase. This enzyme is also called 2-methylserine hydroxymethyltransferase. This enzyme participates in one carbon pool by folate.