| Competition: | Cypriot First Division |
| Season: | 2004–05 |
| Winners: | Anorthosis (12th title) |
| Relegated: | AEP Alki Aris |
| Continentalcup1: | Champions League |
| Continentalcup1 Qualifiers: | Anorthosis (1st qualifying round) |
| Continentalcup2: | UEFA Cup |
| Continentalcup2 Qualifiers: | APOEL (1st qualifying round) AC Omonia (1st qualifying round; via Cypriot Cup) |
| Continentalcup3: | Intertoto Cup |
| Continentalcup3 Qualifiers: | Olympiakos (1st round) |
| League Topscorer: | Łukasz Sosin (21 goals)[1] |
| Matches: | 181 |
| Total Goals: | 548 |
| Prevseason: | 2003–04 |
| Nextseason: | 2005–06 |
The 2004–05 Cypriot First Division was the 66th season of the Cypriot top-level football league. Anorthosis won their 12th title.
Fourteen teams participated in the 2004–05 Cypriot First Division. All teams played against each other twice, once at their home and once away. The team with the most points at the end of the season crowned champions. The last three teams were relegated to the 2005–06 Cypriot Second Division.
The champions ensured their participation in the 2005–06 UEFA Champions League and the runners-up in the 2005–06 UEFA Cup.
The teams had to declare their interest to participate in the 2005 UEFA Intertoto Cup before the end of the championship. At the end of the championship, the higher placed team among the interested ones participated in the Intertoto Cup (if they had not secured their participation in any other UEFA competition).
Teams received three points for a win, one point for a draw and zero points for a loss.
Anagennisi Deryneia, Onisilos Sotira and Doxa Katokopias were relegated from previous season and played in the 2004–05 Cypriot Second Division. They were replaced by the first three teams of the 2003–04 Cypriot Second Division, Nea Salamina, Aris Limassol and Alki Larnaca.