| Competition: | Cypriot First Division |
| Season: | 1991–92 |
| Winners: | APOEL (15th title) |
| Relegated: | Alki Omonia Ar. |
| Continentalcup1: | Champions League |
| Continentalcup1 Qualifiers: | APOEL (1st round) |
| Continentalcup2: | UEFA Cup |
| Continentalcup2 Qualifiers: | Anorthosis (1st round) |
| Continentalcup3: | Cup Winners' Cup |
| Continentalcup3 Qualifiers: | Apollon (1st round; via Cypriot Cup) |
| League Topscorer: | József Dzurják (21 goals)[1] |
| Matches: | 182 |
| Total Goals: | 540 |
| Prevseason: | 1990–91 |
| Nextseason: | 1992–93 |
The 1991–92 Cypriot First Division was the 53rd season of the Cypriot top-level football league. APOEL won their 15th title.
Fourteen teams participated in the 1991–92 Cypriot First Division. All teams played against each other twice, once at their home and once away. The team with the most points at the end of the season crowned champions. The last two teams were relegated to the 1992–93 Cypriot Second Division. The 12th-placed team faced the 3rd-placed team of the 1991–92 Cypriot Second Division, in a two-legged relegation play-off for one spot in the 1992–93 Cypriot First Division.
The champions ensured their participation in the 1992–93 UEFA Champions League and the runners-up in the 1992–93 UEFA Cup.
Teams received three points for a win, one point for a draw and zero points for a loss.
APOP Paphos and APEP were relegated from previous season and played in the 1991–92 Cypriot Second Division. They were replaced by the first two teams of the 1990–91 Cypriot Second Division, Evagoras Paphos and Omonia Aradippou.
The 12th-placed team Olympiakos faced the 3rd-placed team of the 1991–92 Cypriot Second Division APEP, in a two-legged play-off for one spot in the 1992–93 Cypriot First Division. Olympiakos won both matches and secured their place in the 1992–93 Cypriot First Division.