| Competition: | Cypriot First Division |
| Season: | 1979–80 |
| Winners: | APOEL (12th title) |
| Continentalcup1: | European Cup |
| Continentalcup1 Qualifiers: | APOEL (1st round) |
| Continentalcup2: | UEFA Cup |
| Continentalcup2 Qualifiers: | Pezoporikos (1st round) |
| Continentalcup3: | Cup Winners' Cup |
| Continentalcup3 Qualifiers: | Omonia (1st round; via Cypriot Cup) |
| League Topscorer: | Sotiris Kaiafas (23 goals)[1] |
| Matches: | 210 |
| Total Goals: | 537 |
| Prevseason: | 1978–79 |
| Nextseason: | 1980–81 |
The 1979–80 Cypriot First Division was the 41st season of the Cypriot top-level football league.
It was contested by 15 teams, and APOEL F.C. won the championship.