See main article: Cycling at the 2010 South American Games. The Men's Madison event at the 2010 South American Games was held on March 21.
| width=200 bgcolor=gold | Gold | width=200 bgcolor=silver | Silver | width=200 bgcolor=CC9966 | Bronze |
| Carlos Quishpe Bayron de la Cruz | Sebastian Donadio Walter Pérez | Carlos Ospina Weimar Roldán |
Distance: 140 laps (35 km) with 7 sprint
Elapsed time: 43:20.170
Average Speed: 48.458 km/h
| Rank | Rider | Sprint | Finish | Total | Laps Down | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| width=30 | 1 ! | width=30 | 2 ! | width=30 | 3 ! | width=30 | 4 ! | width=30 | 5 ! | width=30 | 6 ! | width=30 | 7 |
Carlos Quishpe Bayron de la Cruz | 5 | 0 | |||||||||||
Sebastian Donadio Walter Pérez | 5 | 3 | 2 | 5 | 5 | 1 | 20 | –1 | |||||
Carlos Ospina Weimar Roldán | 3 | 3 | 5 | 1 | 2 | 2 | 3 | 2 | 19 | –1 | |||
| 4 | Maximo Rojas Yosvangs Rojas | 2 | 2 | 1 | 3 | 5 | 3 | 2 | 3 | 18 | –1 | ||
| 5 | Luis Sepulveda Villar Gonzalo Figueroa | 5 | 1 | 2 | 3 | 1 | 1 | 4 | 13 | –1 | |||
| 6 | Edgard Nicolas Palma Milton Wynants | 5 | 5 | –1 | |||||||||
| 7 | Thiago Nardin Marcos Novello | 1 | 1 | 2 | –1 | ||||||||