CNGB1 explained

Cyclic nucleotide gated channel beta 1, also known as CNGB1, is a human gene encoding an ion channel protein.^[1]

See also

• Cyclic nucleotide-gated ion channel

Further reading

• Hofmann F, Biel M, Kaupp UB . International Union of Pharmacology. LI. Nomenclature and structure-function relationships of cyclic nucleotide-regulated channels. . Pharmacol. Rev. . 57 . 4 . 455–62 . 2006 . 16382102 . 10.1124/pr.57.4.8 . 45853869 .
• Kondo H, Qin M, Mizota A . A homozygosity-based search for mutations in patients with autosomal recessive retinitis pigmentosa, using microsatellite markers. . Invest. Ophthalmol. Vis. Sci. . 45 . 12 . 4433–9 . 2005 . 15557452 . 10.1167/iovs.04-0544 . etal. free .
• Trudeau MC, Zagotta WN . Mechanism of calcium/calmodulin inhibition of rod cyclic nucleotide-gated channels. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 12 . 8424–9 . 2002 . 12048242 . 10.1073/pnas.122015999 . 123083 . 2002PNAS...99.8424T . free .
• Poetsch A, Molday LL, Molday RS . The cGMP-gated channel and related glutamic acid-rich proteins interact with peripherin-2 at the rim region of rod photoreceptor disc membranes. . J. Biol. Chem. . 276 . 51 . 48009–16 . 2002 . 11641407 . 10.1074/jbc.M108941200 . free .
• Bareil C, Hamel CP, Delague V . Segregation of a mutation in CNGB1 encoding the beta-subunit of the rod cGMP-gated channel in a family with autosomal recessive retinitis pigmentosa. . Hum. Genet. . 108 . 4 . 328–34 . 2001 . 11379879 . 10.1007/s004390100496 . 42042382 . etal.
• Pogacić V, Dragon F, Filipowicz W . Human H/ACA small nucleolar RNPs and telomerase share evolutionarily conserved proteins NHP2 and NOP10. . Mol. Cell. Biol. . 20 . 23 . 9028–40 . 2000 . 11074001 . 10.1128/MCB.20.23.9028-9040.2000 . 86556 .
• Körschen HG, Beyermann M, Müller F . Interaction of glutamic-acid-rich proteins with the cGMP signalling pathway in rod photoreceptors. . Nature . 400 . 6746 . 761–6 . 1999 . 10466724 . 10.1038/23468 . 1999Natur.400..761K . 4394997 . etal.
• Ardell MD, Aragon I, Oliveira L . The beta subunit of human rod photoreceptor cGMP-gated cation channel is generated from a complex transcription unit. . FEBS Lett. . 389 . 2 . 213–8 . 1996 . 8766832 . 10.1016/0014-5793(96)00588-1 . 37174534 . etal. free . 1996FEBSL.389..213A .
• Chen TY, Peng YW, Dhallan RS . A new subunit of the cyclic nucleotide-gated cation channel in retinal rods. . Nature . 362 . 6422 . 764–7 . 1993 . 7682292 . 10.1038/362764a0 . 1993Natur.362..764C . 4350775 . etal.
• Ardell MD, Makhija AK, Oliveira L . cDNA, gene structure, and chromosomal localization of human GAR1 (CNCG3L), a homolog of the third subunit of bovine photoreceptor cGMP-gated channel. . Genomics . 28 . 1 . 32–8 . 1995 . 7590744 . 10.1006/geno.1995.1102 . etal.
• Chen TY, Illing M, Molday LL . Subunit 2 (or beta) of retinal rod cGMP-gated cation channel is a component of the 240-kDa channel-associated protein and mediates Ca(2+)-calmodulin modulation. . Proc. Natl. Acad. Sci. U.S.A. . 91 . 24 . 11757–61 . 1994 . 7526403 . 10.1073/pnas.91.24.11757 . 45311 . 1994PNAS...9111757C . etal. free .
• Fujii Y, Zhao FX, Fu SC . Stable preparation of aldose reductase isoenzymes from human placenta. . Protein Expr. Purif. . 2 . 5–6 . 420–5 . 1992 . 1821816 . 10.1016/1046-5928(91)90103-P . etal.

External links

• GeneReviews/NCBI/NIH/UW entry on Retinitis Pigmentosa Overview

Notes and References

1. Web site: Entrez Gene: CNGB1 cyclic nucleotide gated channel beta 1.