Cyanide hydratase explained

cyanide hydratase
Ec Number:	4.2.1.66
Cas Number:	37292-83-4
Go Code:	0030196

The enzyme cyanide hydratase catalyzes the chemical reaction

formamide

\rightleftharpoons cyanide + H₂O

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is formamide hydro-lyase (cyanide-forming). Other names in common use include formamide dehydratase, and formamide hydro-lyase.^[1] This enzyme participates in cyanoamino acid metabolism.

References

• Fry WE, Millar RL . 1972 . Cyanide degradion by an enzyme from Stemphylium loti . Arch. Biochem. Biophys. . 151 . 468 - 74 . 5065258 . 10.1016/0003-9861(72)90523-1 . 2 .

Notes and References

1. Gupta . Neha . Balomajumder . Chandrajit . Agarwal . V. K. . 2010-04-15 . Enzymatic mechanism and biochemistry for cyanide degradation: A review . Journal of Hazardous Materials . 176 . 1 . 1–13 . 10.1016/j.jhazmat.2009.11.038 . 0304-3894.