List of immunofluorescence findings for autoimmune bullous conditions explained

Several cutaneous conditions can be diagnosed with the aid of immunofluorescence studies.

Cutaneous conditions with positive direct or indirect immunofluorescence when using salt-split skin include:

Antibody isotype(s) and location of antibody deposition in immunofluorescence studies using salt-split skin for autoimmune bullous conditions targeting the basement membrane zone of the human integumentary system

Condition	Antibody isotype(s) deposited	Localization of antibody with use of salt-split skin
	IgG	Dermal
		Dermal
		Epidermal
	IgG	Epidermal
	IgG	Dermal
		Epidermal
	IgG	Dermal
	IgG	Epidermal

For several subtypes of pemphigus a variety of substrates are used for indirect immunofluorescence:

Substrates used in indirect immunofluorescence studies for the different pemphigus variants

Pemphigus variant	Substrate
	Guinea pig esophagus
	Monkey esophagus
	Cultured skin
	Rat bladder

See also

• List of cutaneous conditions
• List of genes mutated in cutaneous conditions
• List of cutaneous conditions caused by mutations in keratins

References

• Book: Bolognia, Jean L.. Dermatology . Mosby . St. Louis . 2007 . 1-4160-2999-0 . etal.
• Book: James, William D.. Andrews' Diseases of the Skin: Clinical Dermatology . Saunders Elsevier . 2006 . 0-7216-2921-0 . etal.