List of immunofluorescence findings for autoimmune bullous conditions explained

See also: List of cutaneous conditions.

Several cutaneous conditions can be diagnosed with the aid of immunofluorescence studies.

Cutaneous conditions with positive direct or indirect immunofluorescence when using salt-split skin include:

Antibody isotype(s) and location of antibody deposition in immunofluorescence studies using salt-split skin for autoimmune bullous conditions targeting the basement membrane zone of the human integumentary system

Condition	Antibody isotype(s) deposited	Localization of antibody with use of salt-split skin
	IgG	Dermal
		Dermal
		Epidermal
	IgG	Epidermal
	IgG	Dermal
		Epidermal
	IgG	Dermal
	IgG	Epidermal

For several subtypes of pemphigus a variety of substrates are used for indirect immunofluorescence:

Substrates used in indirect immunofluorescence studies for the different pemphigus variants

Pemphigus variant	Substrate
	Guinea pig esophagus
	Monkey esophagus
	Cultured skin
	Rat bladder

See also

• List of cutaneous conditions
• List of genes mutated in cutaneous conditions
• List of cutaneous conditions caused by mutations in keratins

References

• Book: Bolognia, Jean L.. Dermatology . Mosby . St. Louis . 2007 . 1-4160-2999-0 . etal.
• Book: James, William D.. Andrews' Diseases of the Skin: Clinical Dermatology . Saunders Elsevier . 2006 . 0-7216-2921-0 . etal.