Cucurbitadienol synthase explained

Cucurbitadienol synthase
Ec Number:	5.4.99.33

Cucurbitadienol synthase (CPQ (gene), (S)-2,3-epoxysqualene mutase (cyclizing, cucurbitadienol-forming)) is an enzyme with systematic name (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, cucurbitadienol-forming).^[1] This enzyme catalyses the following chemical reaction

(3S)-2,3-epoxysqualene

\rightleftharpoons cucurbitadienol

Notes and References

1. Cucurbitadienol synthase, the first committed enzyme for cucurbitacin biosynthesis, is a distinct enzyme from cycloartenol synthase for phytosterol biosynthesis . Shibuya M, Adachi S, Ebizuka Y . Tetrahedron . 2004 . 60 . 33 . 6995–7003 . 10.1016/j.tet.2004.04.088.