Cucurbitacin D Explained

Cucurbitacin D is a plant triterpene first identified in plants in the family Cucurbitaceae.[1] [2] In preliminary in vitro studies, it has shown inhibitory properties against endometrial and ovarian cancer cell lines.[3]

Notes and References

  1. 10.1002/jsfa.2740050904 . Bitter principles of the cucurbitaceae. I.—Observations on the chemistry of cucurbitacin A . 1954 . Enslin . P. R. . Journal of the Science of Food and Agriculture . 5 . 9 . 410–416 .
  2. 10.1021/ja01536a047 . The Constituents of Ecballium elaterium L. III. Elatericin a and B1,2 . 1958 . Lavie . David . Willner . David . Journal of the American Chemical Society . 80 . 3 . 710–714 .
  3. 10.1007/s13277-012-0549-2 . 23150173 . Cucurbitacin D induces growth inhibition, cell cycle arrest, and apoptosis in human endometrial and ovarian cancer cells . 2013 . Ishii . Terukazu . Kira . Naoko . Yoshida . Toshie . Narahara . Hisashi . Tumor Biology . 34 . 1 . 285–291 . 16889635 .

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