Cubebol synthase explained

Cubebol synthase
Ec Number:	4.2.3.91

Cubebol synthase (EC 4.2.3.91, Cop4) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, cubebol-forming).^[1] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate + H₂O

\rightleftharpoons cubebol + diphosphate

This enzyme requires Mg²⁺.

Notes and References

1. Lopez-Gallego F, Agger SA, Abate-Pella D, Distefano MD, Schmidt-Dannert C . Sesquiterpene synthases Cop4 and Cop6 from Coprinus cinereus: catalytic promiscuity and cyclization of farnesyl pyrophosphate geometric isomers . ChemBioChem . 11 . 8 . 1093–106 . May 2010 . 20419721 . 2873112 . 10.1002/cbic.200900671 .