| Cruz Grande | |
| Settlement Type: | Municipal seat and city |
| Pushpin Map: | Mexico Guerrero#Mexico |
| Pushpin Label Position: | above |
| Pushpin Mapsize: | 300 |
| Pushpin Map Caption: | Location in Mexico |
| Subdivision Type: | Country |
| Subdivision Name: |  Mexico |
| Subdivision Type1: | State |
| Subdivision Name1: | Guerrero |
| Subdivision Type2: | Municipality |
| Subdivision Name2: | Florencio Villarreal |
| Population As Of: | 2005 |
| Population Blank1 Title: | Ethnicities |
| Population Blank2 Title: | Religions |
| Timezone: | Zona Centro |
| Utc Offset: | -6 |
| Coordinates: | 16.7333°N -107°W |
Cruz Grande is a city and seat of the municipality of Florencio Villarreal, in the southern Mexican state of Guerrero.[1]