Janssen Vaccines Explained

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Janssen Vaccines
Former Name:Crucell
Type:Subsidiary
Hq Location:Archimedesweg 4
Hq Location City:Leiden
Hq Location Country:Netherlands
Industry:Biotechnology
Products:Vaccines and antibodies
Parent:Johnson & Johnson

Janssen Vaccines, formerly Crucell, is a biotechnology company specializing in vaccines and biopharmaceutical technologies.It was formed when Johnson & Johnson acquired the Dutch biotech company Crucell based in Leiden and placed it in their pharmaceutical division.__TOC__

History

In 1993 Introgene, Crucell’s predecessor, was established as a spin-off of Leiden University. The company formed a partnership with Genzyme to collaborate on its vector technology and viral-based products. In 1999 the company founded Galapagos Genomics as a joint venture together with Tibotec. In 2000 IntroGene acquired U-Bisys to form Crucell.

In 2006, Crucell and Swiss Berna Biotech; Swedish SBL Vaccines and US-based Berna Products joined forces to become the sixth largest vaccine company worldwide, with their own clinical programs.

On 7 January 2009 Crucell released a press release saying Crucell and Wyeth were in discussion on a merger of the two companies. On 26 January 2009 Crucell released another press release saying the discussions on a combination of Crucell and Wyeth was discontinued due to Pfizer's acquisition of Wyeth.

In September 2009 Johnson & Johnson bought 18% stake in Crucell for €302 million in order to collaborate on the development of a flu vaccine.[1] This followed Crucell's discovery of CR6261, a potent human antibody that neutralizes a broad range of influenza A viruses. J&J acquired the rest of the company in October 2010, taking its stake to over 95% by February 2011[2] [3] and delisting the company from stock exchanges two months later.[4]

After the takeover by Johnson & Johnson in 2011, Crucell was assigned to Janssen Pharmaceuticals division. In 2014, the subsidiary was renamed from Crucell to Janssen Vaccines.[5] [6]

COVID-19 vaccine development

See main article: article and Janssen COVID-19 vaccine. Janssen Vaccines in Leiden developed the COVID-19 vaccines for Johnson & Johnson. Initial production of the vaccine is happening at Janssen Biotech in Leiden, Netherlands. The vaccine stands out because it is the first single-shot vaccine against COVID-19 that was developed during the COVID-19 pandemic.

References

  1. News: Johnson & Johnson buys 18 pct stake in Crucell . . Gray-Block . Aaron . 28 September 2009 . 28 September 2009.
  2. News: Solsman. Joan E.. J&J: Sufficient Number Of Crucell Holders Tender Shares. 27 February 2011. The Wall Street Journal. 17 February 2011. Dow Jones Newswires.
  3. Web site: J&J aiming to buy vaccine maker Crucell for $2.3 billion . Reuters . en . 17 September 2010.
  4. News: Gray-Block. Aaron. Crucell to be delisted after J&J buyout. 16 April 2011. 11 April 2011. Reuters.
  5. Web site: Crucell . DevEx . 2015 .
  6. Web site: Janssen Vaccines AG . Bloomberg . Company Profiles . 2020 .