| Crown Prince Frederik Island | |
| Pushpin Map: | Canada Nunavut#Canada |
| Native Name Link: | Inuktitut |
| Location: | Gulf of Boothia |
| Coordinates: | 70.0333°N -136°W |
| Archipelago: | Arctic Archipelago |
| Area Km2: | 401 |
| Country: | Canada |
| Country Admin Divisions Title: | Territory |
| Country Admin Divisions: | Nunavut |
| Country Admin Divisions Title 1: | Region |
| Country Admin Divisions 1: | Qikiqtaaluk |
| Population: | Uninhabited |
Crown Prince Frederik Island (French: Île du Prince-Héritier-Frederik) is an island in Nunavut, Canada. It is located off the southern coast of western Baffin Island, in the Qikiqtaaluk Region's side of the Gulf of Boothia. It has an area of 401km2.