Crotalus durissus cumanensis explained

Crotalus durissus cumanensis is a subspecies of venomous pit viper from Colombia and Venezuela.^[1] They account for 1-3% of all snake bites in Colombia.^{[2] [3] [4]}

Toxin

A bite from Crotalus durissus cumanensis can cause neurotoxicity, systemic myotoxicity, mild edema, acute renal failure and death,^[5] even considered one of the most lethal snake species in Latin America.^[6] These bites are only treatable as of now by antivenom therapy. The toxin is thought to be more potent than that of Crotalus durissus ruruima.^[7]

Notes and References

1. Salazar . Ana M . Aguilar . Irma . Guerrero . Belsy . Girón . María E . Lucena . Sara . Sánchez . Elda E . Rodríguez-Acosta . Alexis . September 2008 . Intraspecies differences in hemostatic venom activities of the South American rattlesnakes, Crotalus durissus cumanensis, as revealed by a range of protease inhibitors . Blood Coagulation & Fibrinolysis . en . 19 . 6 . 525–530 . 10.1097/MBC.0b013e328304e02e . 18685436 . 0957-5235.
2. Pereañez . Jaime Andrés . Núñez . Vitelbina . Huancahuire-Vega . Salomón . Marangoni . Sergio . Ponce-Soto . Luis Alberto . 2009-04-01 . Biochemical and biological characterization of a PLA2 from crotoxin complex of Crotalus durissus cumanensis . Toxicon . 53 . 5 . 534–542 . 10.1016/j.toxicon.2009.01.021 . 19673100 . 0041-0101.
3. Rodríguez-Vargas . Ariadna . Vega . Nohora . Reyes-Montaño . Edgar . Corzo . Gerardo . Neri-Castro . Edgar . Clement . Herlinda . Ruiz-Gómez . Francisco . August 2022 . Intraspecific Differences in the Venom of Crotalus durissus cumanensis from Colombia . Toxins . en . 14 . 8 . 532 . 10.3390/toxins14080532 . free . 2072-6651 . 9416679 . 36006194.
4. Acosta-Peña . Augusto . Núñez . Vitelbina . Pereañez . Jaime Andres . Rey-Suárez . Paola . April 2022 . Immunorecognition and Neutralization of Crotalus durissus cumanensis Venom by a Commercial Antivenom Produced in Colombia . Toxins . en . 14 . 4 . 235 . 10.3390/toxins14040235 . free . 2072-6651 . 9025410 . 35448844.
5. Yoshida-Kanashiro . Erika . Navarrete . Luis F. . Rodríguez-Acosta . Alexis . April 2003 . On the unsual hemorrhagic and necrotic activities caused by the rattlesnake (Crotalus durissus cumanensis) in a Venezuelan patient . Revista Cubana de Medicina Tropical . 55 . 1 . 38–40 . 15849951 . 0375-0760.
6. Céspedes . N. . Castro . F. . Jiménez . E. . Montealegre . L. . Castellanos . A. . Cañas . C. A. . Arévalo-Herrera . M. . Herrera . S. . 2010 . Biochemical comparison of venoms from young Colombian Crotalus durissus cumanensis and their parents . Journal of Venomous Animals and Toxins Including Tropical Diseases . en . 16 . 2 . 268–284 . 10.1590/S1678-91992010000200009 . 1678-9199. free .
7. Cavalcante . Walter Luís Garrido . Ponce-Soto . Luis Alberto . Marangoni . Sérgio . Gallacci . Márcia . 2015-03-15 . Neuromuscular effects of venoms and crotoxin-like proteins from Crotalus durissus ruruima and Crotalus durissus cumanensis . Toxicon . 96 . 46–49 . 10.1016/j.toxicon.2015.01.006 . 25598498 . 2015Txcn...96...46C . 0041-0101.