| Cristino Seriche | |
| Birth Name: | Cristino Seriche Bioko |
| Order: | Prime Minister of Equatorial Guinea |
| President: | Teodoro Obiang |
| Term Start: | 15 August 1982 |
| Term End: | 4 March 1992 |
| Predecessor: | position established |
| Successor: | Silvestre Siale |
| Birth Date: | 15 June 1940 |
| Birth Place: | Bata, Spanish Guinea |
| Death Place: | Sipopo, Equatorial Guinea |
| Party: | PDGE |
Cristino Seriche Bioko (15 June 1940 – 11 June 2024) was an Equatoguinean soldier and politician who was the Prime Minister of Equatorial Guinea from 15 August 1982 to 4 March 1992. He was Second Vice President from December 1981 to 1982.[1] He was a member of the Bubi people.[2] He died on 11 June 2024, at the age of 83.[3]