| Santiago de Coyame | |
| Settlement Type: | Town |
| Pushpin Map: | Mexico |
| Pushpin Label Position: | above |
| Pushpin Mapsize: | 300 |
| Pushpin Map Caption: | Location in Mexico |
| Subdivision Type: | Country |
| Subdivision Name: |  Mexico |
| Subdivision Type1: | State |
| Subdivision Name1: | Chihuahua |
| Subdivision Type2: | Municipality |
| Subdivision Name2: | Coyame del Sotol |
| Established Title: | Founded |
| Established Date: | 1715 |
| Unit Pref: | Metric |
| Population As Of: | 2010 |
| Population Total: | 709 |
| Population Blank1 Title: | Ethnicities |
| Population Blank2 Title: | Religions |
| Timezone: | Pacific (US Mountain) |
| Utc Offset: | −7 |
| Timezone Dst: | Pacific |
| Utc Offset Dst: | −6 |
| Coordinates: | 29.4614°N -105.0972°W |
| Elevation M: | 1220 |
| Postal Code Type: | Postal code |
| Postal Code: | 32850 |
| Area Code: | 626 |
| Blank Name: | Demonym |
| Blank Info: | Coyamense |
Coyame (formally: Santiago de Coyame) is a town in the Mexican state of Chihuahua. It serves as the municipal seat of Coyame del Sotol Municipality.
In the 2010 INEGI Census, the town reported a total population of 709. [1]
It was founded in 1715 by the Spanish explorer Juan Antonio Traviña y Retes.
Coyame is also the location of a hot spring and a cave system.