| State: | FL |
| Type: | SR |
| Route: | 345 |
| Map Custom: | yes |
| Map Notes: | SR 345 in red, segments of CR 345 in blue |
| Maint: | FDOT |
| Length Mi: | 7.630 |
| Direction A: | South |
| Terminus A: | at Curryville |
| Junction: | near Chiefland |
| Direction B: | North |
| Terminus B: | near Chiefland |
| Counties: | Levy |
| Previous Type: | SR |
| Previous Route: | 331 |
| Next Type: | SR |
| Next Route: | 349 |
State Road 345 (SR 345) is a north - south route in the Big Bend area of Florida, running from U.S. Route 27 Alternate (US 27 Alt.) east of Chiefland to County Road 332 (CR 332) southwest of Chiefland. South of CR 332, the road becomes County Road 345 as it runs towards Rosewood.[1]
Another piece of CR 345 begins at US 27 Alt. about east of the north end of SR 345 and runs north to the curve on SR 49. A third section goes east from a point about north on SR 49 to CR 339.