| State: | FL |
| Type: | SR |
| Route: | 22 |
| Map Custom: | yes |
| Length Mi: | 25.855 |
| Length Round: | 3 |
| Established: | 1945 |
| Direction A: | West |
| Direction B: | East |
| Terminus A: | in Springfield |
| Junction: | in Callaway |
| Terminus B: | in Wewahitchka |
| Counties: | Bay, Gulf |
| Previous Type: | SR |
| Previous Route: | 21 |
| Next Type: | US |
| Next Route: | 23 |
State Road 22 (SR 22) runs east and west from US 98 Business in Springfield to SR 71 in Wewahitchka. SR 22 is known as East 3rd Street in Springfield and Wewa Highway from Callaway to Wewahitchka. With the exception of the intersection with US 98 in Callaway, SR 22 is entirely a two-lane undivided highway, and is far more rural east of Callaway.
Beginning one block south of SR 22's eastern terminus, County Road 22 (CR 22) extends the route to the banks of the Apalachicola River. Several other disconnected segments of CR 22 exist in the Apalachicola National Forest and other protected areas to the east, evidencing a former plan to extend SR 22 to Sopchoppy via Sumatra.[1]
Beginning at the intersection of State Road No. 22 and State Road No. 71 in the Town of Wewahitchka, said State Road 22 shall run in an east-southeast direction to or near Cockran Landing, thence east-southeastward through the Apalachicola River swamp, crossing the Apalachicola River at a point approximately one-fourth to one-half mile south of the mouth of River Styx, thence run in a general eastward direction approximately four miles, crossing Kennedy Creek in the vicinity of Gibson's Ford to a point immediately north of Greenhead Bay, thence run southeastward via Kirkland's farm to a point immediately east of Rowlett's Creek, thence run in a general east-southeastward direction to a point approximately one-eighth mile south of the northwest corner of Section 30, Township 5 South, Range 7 West, thence run in a general eastward direction to intersect with Eighth Street and Seventh Avenue, Town of Sumatra, thence continue eastward along Eighth Street through the Town of Sumatra, thence continue in a general eastward direction through Liberty County to the Ochlockonee River, crossing the Ochlockonee River in the vicinity of Silver Lake, thence run in a general northeastward direction to or near Sanborn's Fire Tower in Wakulla County, where State Road No. 22 will intersect with State Road No. 375. The right of way for widening said street shall be furnished by Liberty County within ninety (90) days from and after the passage of this Act, and may be acquired by gift, purchase or eminent domain.