| Cota Creek | |
| Subdivision Type1: | Country |
| Subdivision Name1: | United States |
| Subdivision Type2: | State |
| Subdivision Name2: | Iowa |
| Subdivision Type4: | District |
| Subdivision Name4: | Allamakee County |
| Subdivision Type5: | City |
| Subdivision Name5: | Harper's Ferry |
| Discharge1 Location: | Mississippi River |
| Source1 Location: | IA, US |
| Source1 Coordinates: | 43.259°N -91.222°W |
| Mouth Location: | IA, US |
| Mouth Coordinates: | 43.192°N -91.158°W |
Cota Creek is a very minor tributary of the Upper Mississippi River. It is confined mainly to Taylor Township in Allamakee County, Iowa, United States. It joins the river at Harpers Ferry, downstream from Lock and Dam No. 9.