| Costin D. Nenițescu | |
| Birth Date: | 15 July 1902 |
| Birth Place: | Bucharest, Kingdom of Romania |
| Death Place: | Bușteni, Socialist Republic of Romania |
| Resting Place: | Bellu Cemetery, Bucharest |
| Workplaces: | University of Bucharest Politehnica University of Bucharest |
| Alma Mater: | ETH Zurich Ludwig Maximilian University of Munich |
| Thesis Title: | Beitrag zum Aufbau der saueren Spaltprodukte des Blutfarbstoffs |
| Thesis Year: | 1925 |
| Doctoral Advisor: | Hans Fischer |
| Known For: | Nenitzescu indole synthesis |
| Mother: | Elena Nenițescu |
| Relatives: | Ioan S. Nenițescu (uncle) |
Costin D. Nenițescu (in some places Nenitzescu (in Romanian; Moldavian; Moldovan pronounced as /kosˈtin neniˈt͡sesku/; 15 July 1902 – 28 July 1970)) was a prominent Romanian chemist, and a professor at the Politehnica University of Bucharest. He was a titular member of the Romanian Academy, a corresponding member of the German Academy of Sciences in Berlin, and a member of the Leopoldina Academy of Natural Scientists in Halle-Saale.
He was born in Bucharest, the son of (lawyer and politician, director of the National Bank of Romania and Minister of Industry and Commerce)[1] and Elena Nenițescu, and the nephew of the writer Ioan S. Nenițescu.[2] After completing in 1920 his secondary studies at Gheorghe Lazăr High School, Nenițescu continued his studies at the Polytechnic Institute in Zurich and Ludwig Maximilian University in Munich, where he completed in 1935 his Ph.D. under the direction of Hans Fischer,[1] [3] with thesis regarding the synthesis of degradation products of blood pigments.[4] [5]
Upon returning to Romania, he became a professor at the University of Bucharest from 1925 to 1935.[1] He studied Friedel–Crafts-like reactions in the series of aliphatic hydrocarbons, the mechanism of the isomerization of cyclobasics, the halogen migration in cycles and chains, reactions induced by carbonium ions, and others. He identified a group of naphthenic acids in Romanian oil. He searched for ways of obtaining cyclobutadiene, while explaining the chemistry of this unstable substance and isolating its dimers.
His research interests included the oxidation of open-chain and aromatic hydrocarbons with chromic acid and chromic oxychloride. He found new methods for the synthesis of pyrylium salts (Balaban–Nenitzescu–Praill synthesis), of carbenes, tryptamine, serotonin, two new syntheses for the indole nucleus, and a new method of polymerisation of ethylene.[6]
His research was substantiated in more than 200 papers. His remarkable technical and scientific activity helped develop the chemical industry in Romania.[7] A preferred quote is:
"To be able to convey science you have to be yourself a creative scientist, or at least you should strive to be".
Nenițescu was elected corresponding member of the Romanian Academy in 1945 and a titular member in 1955.[8] In 1969, he was nominated for the Nobel Prize in Chemistry "for discovering two new syntheses for the indolenucleus, and a new method of polymerisation of ethylene".[9]
He was married to (1909–2000). A student of his, she obtained her Ph.D. in chemistry in 1936, became a professor at Politehnica University, and was elected titular member of the Romanian Academy in 1974.[8] The family lived in a house located at 8, Strada Școalei, in central Bucharest. Built by his father in 1908 in the Romanian Revival style, the house was declared a historic monument in 2010, but was abandoned soon after and caught fire in 2016.[10] [11]
He died in Bușteni at age 68[1] and was buried at Bellu Cemetery in Bucharest. In his honor, the chemistry contest "C.D. Nenițescu" is organized yearly at the Polytechnic University of Bucharest. The Costin D. Nenițescu Technical College in Pitești bears his name.[12] A street in Sector 6 of Bucharest is also named after him.