Cosimo Commisso (scientist) explained

Cosimo Commisso is a Canadian cell biologist and cancer researcher who has made significant advances in the field of cellular trafficking and cancer metabolism.[1] [2] [3] Among his most notable contributions are the discovery and study of how macropinocytosis supports tumor cell growth and survival by serving as an amino acid supply route in Ras-mutated cancers.[4] [5] [6] He is currently an associate professor in the Tumor Initiation and Maintenance Program at the Sanford Burnham Prebys Medical Discovery Institute NCI-designated Cancer Center in La Jolla, California, USA.

External links

Notes and References

  1. Web site: DR. COSIMO COMMISSO AND THE NUTRIENT SCAVENGERS. Trading. American Laboratory. americanlaboratorytrading.com. en. 2017-11-20.
  2. News: 2015 Grant Recipient Cosimo Commisso, PhD – Pancreatic Cancer Action Network. Pancreatic Cancer Action Network. 2017-11-20. en-US.
  3. News: New understanding of nutrient uptake in Pancreatic Cancer cells could lead to future drug targets · Pancreatic Cancer Action. Action. Pancreatic Cancer. 2013-05-27. Pancreatic Cancer Action. 2017-11-20. en-GB.
  4. Commisso. Cosimo. Davidson. Shawn M.. Soydaner-Azeloglu. Rengin G.. Parker. Seth J.. Kamphorst. Jurre J.. Hackett. Sean. Grabocka. Elda. Nofal. Michel. Drebin. Jeffrey A.. 2013-05-12. Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells. Nature. en. 497. 7451. 633–637. 10.1038/nature12138. 23665962. 3810415. 1476-4687.
  5. Kamphorst. Jurre J.. Nofal. Michel. Commisso. Cosimo. Hackett. Sean R.. Lu. Wenyun. Grabocka. Elda. Vander Heiden. Matthew G.. Miller. George. Drebin. Jeffrey A.. 2015-02-01. Human Pancreatic Cancer Tumors Are Nutrient Poor and Tumor Cells Actively Scavenge Extracellular Protein. Cancer Research. 75. 3. 544–553. 10.1158/0008-5472.can-14-2211. 25644265. 4316379.
  6. Commisso. Cosimo. Flinn. Rory J. Bar-Sagi. Dafna. 2014-01-02. Determining the macropinocytic index of cells through a quantitative image-based assay. Nature Protocols. en. 9. 1. 182–192. 10.1038/nprot.2014.004. 24385148. 1750-2799. 4103788.

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