Corynebacterial porin B explained

Symbol:PorB
PorB
Pfam:PF11565
Interpro:IPR021114
Tcdb:1.B.34
Opm Family:190
Opm Protein:2vql

Porins B and C are cell wall channel-forming proteins from Corynebacterium. Porin B from Corynebacterium glutamicum (Brevibacterium flavum) allows the exchange of material across the mycolic acid layer, which is the protective nonpolar barrier. Porin B has an alpha helical core structure consisting of four alpha-helices surrounding a nonpolar interior. There is a disulfide bridge between helices 1 and 4 to form a stable covalently bound ring.[1] The channel of PorB is oligomeric.[1]

Notes and References

  1. Ziegler K, Benz R, Schulz GE . A putative alpha-helical porin from Corynebacterium glutamicum . J. Mol. Biol. . 379 . 3 . 482–91 . June 2008 . 18462756 . 10.1016/j.jmb.2008.04.017 .