Corydalis ambigua explained

Corydalis ambigua is a tuberous early flowering east Asian flowering plant species in the poppy family Papaveraceae. Its exact native range is obscure due to taxonomic confusion. It is one of the sources of the drug tetrahydropalmatine.

Chemistry

Corydalis ambigua contains a variety of alkaloids including corynoline, acetylcorynoline, d-corydalin, dl-tetrahydropalmatine, protopine, tetrahydrocoptisine, dl-tetrahydrocoptisine, d-corybulbine and allocryptopine.^{[1] [2] [3] [4]}

Chemical derivatives of present in Corydalis ambigua have been studied as potential ways to increase pain tolerance and for treating drug addiction.^[5] Further, they may represent a category of neurotransmitter stabilizers which have potential use in broad range of psychotic and neurological disorders.^[5]

Use

Cordyalis ambigua is part of the traditional Ainu cuisine:

See also

• Chinese herbology

Further reading

• Bhakuni. D. S.. Chaturvedi. Rekha. The Alkaloids of Corydalis meifolia. Journal of Natural Products. 46. 466–70. 1983. 10.1021/np50028a006. 4. 6631434.

Notes and References

1. IDENTIFICATION OF THE STRUCTURES OF CORYDALIS F, I, J AND K . Acta Chimica Sinica . 1981 . Zhu, Da-Yuan . etal . 2010-10-08 . 2014-02-02 . https://web.archive.org/web/20140202153012/http://en.cnki.com.cn/Article_en/CJFDTOTAL-HXXB198103013.htm . dead .
2. Ma, W.g. . Fukushi, Y. . Tahara, S. . 1999 . Fungitoxic alkaloids from Hokkaido Corydalis species . Fitoterapia . 70 . 3 . 258–265 . 10.1016/S0367-326X(99)00045-3.
3. Alkaloid production by somatic embryo cultures of Corydalis ambigua. Hiraoka, Noboru. Plant Biotechnology . 21 . 5 . 361–366 . 2004. 10.5511/plantbiotechnology.21.361. etal. free.
4. Zhu. Xing-Zu. Memórias do Instituto Oswaldo Cruz - Development of natural products as drugs acting on central nervous system. Memórias do Instituto Oswaldo Cruz. 86. 1991 . 10.1590/S0074-02761991000600039. 173. 1841995. free.
5. Zhen X.-C. . 2010 . Tetrahydroprotoberberines (THPBs) in neuropsychological disorders: Recent development and prospective (Abstract S-33.004) . International Journal of Neuropsychopharmacology . 13 . SUPPL. 1 . 41.