| Tourney Name: | Copa Mercosur |
| Yearr: | 2000 |
| Dates: | 1 August – 20 December 2000 |
| Num Teams: | 20 |
| Associations: | 5 |
| Champion Other: |  Vasco da Gama |
| Count: | 1 |
| Second Other: | Palmeiras |
| Matches: | 75 |
| Goals: | 239 |
| Top Scorer: | Romário (11 goals) |
| Prevseason: | 1999 |
| Nextseason: | 2001 |
The Copa Mercosur 2000 was the 3rd staging of the international club cup.
The competition started on 1 August 2000 and concluded on 20 December 2000 with Vasco da Gama beating Palmeiras in the final.
| width=125 | Country | width=150 | Team |
|---|---|---|---|
 Argentina(6 berths) | Boca Juniors | ||
| Independiente | |||
| River Plate | |||
| Rosario Central | |||
| San Lorenzo | |||
| Vélez Sársfield | |||
(7 berths) | Atlético Mineiro | ||
| Corinthians | |||
| Cruzeiro | |||
| Flamengo | |||
| Palmeiras | |||
| São Paulo | |||
| Vasco da Gama | |||
(3 berths) | Colo-Colo | ||
| Universidad Católica | |||
| Universidad de Chile | |||
 Paraguay(2 berths) | Cerro Porteño | ||
| Olimpia | |||
(2 berths) | Nacional | ||
| Peñarol | |||
---- ---- ----
River Plate won 6–4 on aggregate.----1–1 on aggregate, Vasco da Gama won 5–4 on penalties.----Palmeiras won 5–3 on aggregate.----Atlético Mineiro won 4–2 on aggregate.
----
Vasco da Gama won 5–1 on aggregate.----Palmeiras won 6–1 on aggregate.
| Copa Mercosur 2000 Winner | |
|---|---|
| |
| Vasco da Gama First Title |