Cooper Creek is a stream in Henry and St. Clair counties of Missouri. It is a tributary of Deepwater Creek within the Truman Reservoir.
The stream headwaters are in St Clair County just west of the community of Ohio at 38.1539°N -93.8697°W. The stream flows to the northeast into Henry County and passes under Missouri Route 13. The confluence with the Deepwater Creek arm of the Truman Reservoir is at 38.265°N -93.7336°W approximately midway between Deepwater to the northwest and Brownington to the southeast.[1]
Cooper Creek bears the name of a pioneer citizen.[2]