| Constancia Mangue | |
| Office: | First Lady of Equatorial Guinea |
| President: | Teodoro Obiang Nguema Mbasogo |
| Term Label: | Assumed role |
| Term Start: | 3 August 1979 |
| Office2: | First Lady of African Union |
| Term Start2: | 31 January 2011 |
| Term End2: | 29 January 2012 |
| President2: | Teodoro Obiang Nguema Mbasogo |
| Predecessor2: | Callista Chimombo |
| Successor2: | Chantal Yayi |
| Birth Date: | 20 August 1952 |
| Birth Place: | Angong-Obuc, Mongomo, Spanish Guinea (now Equatorial Guinea) |
| Children: | 3 (including Teodoro Nguema Obiang Mangue) |
Constancia Mangue Nsue Okomo (born 20 August 1952),[1] also known as Constancia Mangue de Obiang, is the First Lady of Equatorial Guinea. She is the wife of President Teodoro Obiang Nguema Mbasogo and mother of First Vice President Teodoro Nguema Obiang Mangue.