| CUS | |
| Location Country: | Nicaragua |
| Affiliation: | ITUC |
| Members: | 21,000 |
| Full Name: | Confederation of Labour Unification |
| Native Name: | Confederación de Unificación Sindical |
| Founded: | 1964 |
| Headquarters: | Managua, Nicaragua |
The Confederación de Unificación Sindical ('Confederation of Trade Union Unity', CUS) is a national trade union center in Nicaragua. It was formed in 1964 as the Nicaraguan Trade Union Council (CSN).
ICTUR reports that following the Sandinista revolution the CUS rapidly diminished - a result of its involvement with the previous government.
The CUS is affiliated with the International Trade Union Confederation.