Conasprella spirofilis is a species of sea snail, a marine gastropod mollusk in the family Conidae, the cone snails and their allies.
Like all species within the genus Conasprella, these cone snails are predatory and venomous. They are capable of "stinging" humans, therefore live ones should be handled carefully or not at all.
The size of the shell varies between 19 mm and 37 mm.
This marine species occurs off the Philippines and Japan.