Compound 48/80 Explained

Compound 48/80 is a polymer produced by the condensation of N-methyl-p-methoxyphenethylamine with formaldehyde. It promotes histamine release,[1] and in biochemical research, compound 48/80 is used to promote mast cell degranulation.[2]

Notes and References

  1. Br J Pharmacol . 1970 . 38 . 1 . 253–262 . Mechanisms of histamine release by compound 48/80 . A. M. Rothschild . 4189829 . 1702640 . 10.1111/j.1476-5381.1970.tb10354.x.
  2. 10.1371/journal.pone.0052104. 23272218. The Mast Cell Degranulator Compound 48/80 Directly Activates Neurons. PLOS ONE. 7. 12. e52104. 2012. Schemann. Michael. Kugler. Eva Maria. Buhner. Sabine. Eastwood. Christopher. Donovan. Jemma. Jiang. Wen. Grundy. David. 3525567. 2012PLoSO...752104S. free.

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