Comamonas testosteroni explained

Comamonas testosteroni is a Gram-negative environmental bacterium capable of utilizing testosterone as a carbon source, and degrading other sterols such as ergosterol and estrogens.^[1] Strain I2gfp has been used in bioaugmentation trials, in attempts to treat the industrial byproduct 3-chloroaniline.^[2] It was first classified as a human pathogen in 1987 according to the National Library of Medicine. A number of strains of Comamonas, including C. testosteroni, have been shown to consume terephthalic acid, one of the components of PET plastic, as a sole carbon source.^[3]

Virulence

Though these organisms have low virulence, they can occasionally cause human diseases. They can be found in intravenous catheters, the respiratory tract, abdomen, urinary tract, and the central nervous system. Symptoms of infection may variously include vomiting, watery diarrhea, and meningitis.^[4]

External links

• Web site: Comamonas testosteroni | Type strain | DSM 50244, ATCC 11996, ICPB 2741-78, NCIB 8955, CCUG 1426, NRRL B-2611, NCTC 10698, LMG 1786, JCM 5832, BCRC 11023, BCRC 14822, CCM 1931, CECT 326, CIP 59.24, HAMBI 403, IAM 12419, IFO 14951, JCM 6221, KCTC 1772, LMG 1800, NBRC 14951, NCAIM B.01655, NCAIM B.01926, NCIMB 8955, NCPPB 1969, VKM B-1241, VTT E-86249 | BacDiveID:2923 .

Notes and References

1. Liu . Na . Shi . Yue-e . Li . Jialu . Zhu . Meiling . Zhang . Tingdi . Identification and genome analysis of Comamonas testosteroni strain JLU460ET, a novel steroid-degrading bacterium . 3 Biotech . September 2021 . 11 . 9 . 404 . 10.1007/s13205-021-02949-8 . 8353041 . 34458066 .
2. Boon . Nico . Goris . Johan . De Vos . Paul . Verstraete . Willy . Top . Eva M. . Bioaugmentation of Activated Sludge by an Indigenous 3-Chloroaniline-Degrading Comamonas testosteroni Strain, I2 gfp . Applied and Environmental Microbiology . July 2000 . 66 . 7 . 2906–2913 . 10.1128/AEM.66.7.2906-2913.2000 . 10877785 . 92090 . 2000ApEnM..66.2906B .
3. Schläfli . H R . Weiss . M A . Leisinger . T . Cook . A M . November 1994 . Terephthalate 1,2-dioxygenase system from Comamonas testosteroni T-2: purification and some properties of the oxygenase component . Journal of Bacteriology . en . 176 . 21 . 6644–6652 . 10.1128/jb.176.21.6644-6652.1994 . 0021-9193 . 197021 . 7961417.
4. Farooq . Shaika . Farooq . Rumana . Nahvi . Nahida . Comamonas testosteroni: Is It Still a Rare Human Pathogen . Case Reports in Gastroenterology . 31 January 2017 . 11 . 1 . 42–47 . 10.1159/000452197 . 5301100 . 28203137 .