| Comalcalco | |
| Motto: | "La Perla de la Chontalpa" |
| Pushpin Label Position: | above |
| Pushpin Map Caption: | Location in Mexico |
| Subdivision Type: | Country |
| Subdivision Name: |  Mexico |
| Subdivision Type1: | State |
| Subdivision Name1: | Tabasco |
| Subdivision Type2: | Capital |
| Government Type: | Gregorio Efrain Espadas Méndez |
| Population As Of: | 2020 |
| Population Total: | 214 877 |
| Timezone: | Central Standard Time |
| Utc Offset: | -6 |
| Timezone Dst: | Central Daylight Time |
| Utc Offset Dst: | -5 |
| Elevation M: | 5 and 13 |
Comalcalco is a municipality in the Mexican state of Tabasco in south-eastern Mexico.[1]