Colterol Explained

Iupac Name:	4-[2-(''tert''-Butylamino)-1-hydroxyethyl]benzene-1,2-diol
Cas Number:	18866-78-9
Unii:	1WH11068UO
Pubchem:	25104
Chemspiderid:	23451
Synonyms:	N-tert-Butylarterenol; N-tert-Butylnoradrenaline
C:	12
H:	19
N:	1
O:	3
Stdinchi:	1S/C12H19NO3/c1-12(2,3)13-7-11(16)8-4-5-9(14)10(15)6-8/h4-6,11,13-16H,7H2,1-3H3
Stdinchikey:	PHSMOUBHYUFTDM-UHFFFAOYSA-N
Smiles:	CC(C)(C)NCC(C1=CC(=C(C=C1)O)O)O

Colterol is a short-acting β2-adrenoreceptor agonist. Bitolterol, a prodrug for colterol,^[1] is used in the management of bronchospasm in asthma and chronic obstructive pulmonary disease (COPD).

Patents:^{[2] [3]}

Notes and References

1. Walker SB, Kradjan WA, Bierman CW . Bitolterol mesylate: a beta-adrenergic agent. Chemistry, pharmacokinetics, pharmacodynamics, adverse effects and clinical efficacy in asthma . Pharmacotherapy . 5 . 3 . 127–37 . 6 May 1985 . 3895171 . 10.1002/j.1875-9114.1985.tb03410.x . 29431526 .
2. Aktiengesellschaft F Hoffmann, CH263801 (1949-09-15 to Hoffmann La Roche).
3. Yasuo Konishi, Joanne Magoon, Suwatchai Jarussophon, WO2008092257 (2008 to National Research Council Of Canada). Location in patent: Page column 17.