Colloid nodule explained

Colloid nodules, also known as adenomatous nodules[1] or colloid nodular goiter[2] are benign, noncancerous enlargement of thyroid tissue.[3] Although they may grow large, and there may be more than one, they are not malignant and they will not spread beyond the thyroid gland. Colloid nodules are the most common kind of thyroid nodule.[4]

Presentation

Colloid nodules are usually small enough to be undetectable without an ultrasound or other imaging techniques.[5] They usually produce no symptoms, so patients are unlikely to notice them until their size makes them easier to detect. Like other thyroid nodules, they are usually first noticed in a routine physical examination.[6]

Diagnosis

Colloid nodules may be initially identified as an unspecified kind of thyroid nodule. Follow-up examinations typically include an ultrasound if it is unclear whether or not there really is a nodule present. Once the presence of a nodule has been confirmed, the determination of the kind of thyroid nodule is done by fine needle aspiration biopsy.[7]

Colloid nodules are distinguished by an apparently gelatinous mass of colloid both surrounding and contained within follicular cells. Colloid nodules are not surrounded by a fibrous capsule of compressed tissue. However, they are surrounded by flattened epithelial cells.[8] Both the number of cells and the type of colloid may vary considerably.[7]

Treatment

No treatment is generally needed. Treatment may be indicated if follow up exams show significant change.[9]

See also

External links

Notes and References

  1. Web site: Ultrasound images of diseases of thyroid gland . Joe Antony, MD . 11 June 2011 . medicalonly.com . 26 September 2011 . dead . https://web.archive.org/web/20110923202159/http://www.ultrasound-images.com/thyroid.htm . 23 September 2011 .
  2. Web site: Colloid Nodular Goiter . A.D.A.M. Health Solutions . 17 June 2008. The New York Times. 4 January 2012. A.D.A.M., Inc .
  3. Web site: Diseases & Conditions: Thyroid Nodules . 10 August 2010 . thyroidmanager.org . 26 September 2011.
  4. Thyroid Nodules . American Family Physician . 67 . 3 . 559–566 . 1 February 2003. medicalonly.com . 26 September 2011. Orlov . Diane . Welker . Mary Jo . 12588078 .
  5. Web site: The Truth About Thyroid Growths: Origins, Symptoms, and Outcomes . 21 June 2007 . American Academy of Family Physicians . 26 September 2011 . https://web.archive.org/web/20110518155928/http://www.medicalonly.com/2007/06/21/thyroid_growths . 18 May 2011 . dead .
  6. Web site: Thyroid nodule . 19 April 2010. Medline Plus . 26 September 2011.
  7. Web site: Fine-Needle Aspiration Biopsy of the Thyroid Gland, Chapter 6d. . Diana S. Dean, M.D. Hossein Gharib, M.D. . 10 October 2010 . thyroidmanager.org . 26 September 2011 . https://web.archive.org/web/20111005123832/http://www.thyroidmanager.org/chapter%206d/fnabiopsy-frame.htm . 5 October 2011 . dead .
  8. Web site: Thyroid cytology . Dr. Alpha Tsui . 10 October 2010 . thyroidmanager.org . 26 September 2011 . https://web.archive.org/web/20120405065332/http://rcpa.tv/parts/educational/anatomical/Dr_Alpha_Tsui/Thyroid_cytology.pdf . 5 April 2012 . dead .
  9. Web site: UpToDate. www.uptodate.com. 2018-06-04.

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