Collagen, type XIV, alpha 1 explained

Collagen alpha-1(XIV) chain is a protein that in humans is encoded by the COL14A1 gene.^{[1] [2] [3]} It likely plays a role in collagen binding and cell-cell adhesion.^[4]

Further reading

• Schuppan D, Cantaluppi MC, Becker J . Undulin, an extracellular matrix glycoprotein associated with collagen fibrils. . J. Biol. Chem. . 265 . 15 . 8823–32 . 1990 . 10.1016/S0021-9258(19)38962-8 . 2187872 . etal. free .
• Schnittger S, Herbst H, Schuppan D . Localization of the undulin gene (UND) to human chromosome band 8q23. . Cytogenet. Cell Genet. . 68 . 3–4 . 233–4 . 1995 . 7842743 . 10.1159/000133920. etal.
• Casini A, Ceni E, Salzano R . Regulation of undulin synthesis and gene expression in human fat-storing cells by acetaldehyde and transforming growth factor-beta 1: comparison with fibronectin. . Biochem. Biophys. Res. Commun. . 199 . 2 . 1019–26 . 1994 . 8135774 . 10.1006/bbrc.1994.1331 . etal.
• Tono-Oka S, Tanase S, Miike T, Tanaka H . Transient expression of collagen type XIV during muscle development and its reappearance after denervation and degeneration. . J. Histochem. Cytochem. . 44 . 8 . 907–18 . 1996 . 8756762 . 10.1177/44.8.8756762. free .
• Ehnis T, Dieterich W, Bauer M . A chondroitin/dermatan sulfate form of CD44 is a receptor for collagen XIV (undulin). . Exp. Cell Res. . 229 . 2 . 388–97 . 1997 . 8986622 . 10.1006/excr.1996.0384 . etal.
• Göpel C, Schultka R, Schuppan D . [Age-dependent distribution of collagen and glycoproteins in the blood vessels of the human uterine tube] . Ann. Anat. . 179 . 1 . 83–8 . 1997 . 9092299 . 10.1016/S0940-9602(97)80144-6.
• Ehnis T, Dieterich W, Bauer M . Localization of a binding site for the proteoglycan decorin on collagen XIV (undulin). . J. Biol. Chem. . 272 . 33 . 20414–9 . 1997 . 9252349 . 10.1074/jbc.272.33.20414. etal. free .
• Imhof M, Trueb B . Comparative cytogenetic mapping of COL14A1, the gene for human and mouse collagen XIV. . Cytogenet. Cell Genet. . 84 . 3–4 . 217–9 . 1999 . 10393435 . 10.1159/000015262. 24286993 .
• Fukushima M, Hirano S, Tanaka H . Dorsoventral differential distribution of collagen type XIV around the spinal cord is regulated by the ectoderm. . Dev. Growth Differ. . 41 . 6 . 751–8 . 2000 . 10646805 . 10.1046/j.1440-169x.1999.00472.x. 32320869 . free .
• Strausberg RL, Feingold EA, Grouse LH . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241. 2002PNAS...9916899M . etal. free .
• Ota T, Suzuki Y, Nishikawa T . Complete sequencing and characterization of 21,243 full-length human cDNAs. . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . etal. free .
• Gerecke DR, Meng X, Liu B, Birk DE . Complete primary structure and genomic organization of the mouse Col14a1 gene. . Matrix Biol. . 22 . 7 . 595–601 . 2004 . 15065570 . 10.1016/j.matbio.2003.11.005.
• Brandenberger R, Wei H, Zhang S . Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. . Nat. Biotechnol. . 22 . 6 . 707–16 . 2005 . 15146197 . 10.1038/nbt971 . 27764390 . etal.
• Gerhard DS, Wagner L, Feingold EA . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928. etal.
• Thierry L, Geiser AS, Hansen A . Collagen types XII and XIV are present in basement membrane zones during human embryonic development. . J. Mol. Histol. . 35 . 8–9 . 803–10 . 2005 . 15609093 . 10.1007/s10735-004-1132-y . 30409158 . etal.
• Ruehl M, Erben U, Schuppan D . The elongated first fibronectin type III domain of collagen XIV is an inducer of quiescence and differentiation in fibroblasts and preadipocytes. . J. Biol. Chem. . 280 . 46 . 38537–43 . 2006 . 16129687 . 10.1074/jbc.M502210200 . etal. free .
• Rual JF, Venkatesan K, Hao T . Towards a proteome-scale map of the human protein-protein interaction network. . Nature . 437 . 7062 . 1173–8 . 2005 . 16189514 . 10.1038/nature04209 . 2005Natur.437.1173R . 4427026 . etal.
• Nusbaum C, Mikkelsen TS, Zody MC . DNA sequence and analysis of human chromosome 8. . Nature . 439 . 7074 . 331–5 . 2006 . 16421571 . 10.1038/nature04406 . 2006Natur.439..331N . etal. free .

Notes and References

1. Just M, Herbst H, Hummel M, Durkop H, Tripier D, Stein H, Schuppan D . Undulin is a novel member of the fibronectin-tenascin family of extracellular matrix glycoproteins . J Biol Chem . 266 . 26 . 17326–32 . Oct 1991 . 10.1016/S0021-9258(19)47377-8 . 1716629 . free .
2. Bauer M, Dieterich W, Ehnis T, Schuppan D . Complete primary structure of human collagen type XIV (undulin) . Biochim Biophys Acta . 1354 . 3 . 183–8 . Jan 1998 . 9427527 . 10.1016/S0167-4781(97)00131-0.
3. Web site: Entrez Gene: COL14A1 collagen, type XIV, alpha 1 (undulin).
4. Web site: COL14A1 - Collagen alpha-1(XIV) chain precursor - Homo sapiens (Human) - COL14A1 gene & protein.