Collaborative Group on Hormonal Factors in Breast Cancer explained

The Collaborative Group on Hormonal Factors in Breast Cancer (CGHFBC) is a group of scientific researchers who conduct meta-analyses of the worldwide epidemiological evidence on risk factors for breast cancer in women. It formed in 1992. Their earliest publications were a 1996 meta-analysis of 54 studies on hormonal birth control and breast cancer risk^[1] and a 1997 meta-analysis of 51 studies on menopausal hormone therapy and breast cancer risk.^[2] One of their recent publications was a 2019 meta-analysis of menopausal hormone therapy and breast cancer risk based on type and timing of therapy.^[3] In 2012, the group concluded in a meta-analysis of 117 studies that the incidence of breast cancer was increased by each year younger at menarche and each year older at menopause.^[4]

Notes and References

1. Breast cancer and hormonal contraceptives: collaborative reanalysis of individual data on 53 297 women with breast cancer and 100 239 women without breast cancer from 54 epidemiological studies . Lancet . 347 . 9017 . 1713–27 . June 1996 . 8656904 . 10.1016/s0140-6736(96)90806-5 . 36136756 . Collaborative Group on Hormonal Factors in Breast Cancer .
2. Breast cancer and hormone replacement therapy: collaborative reanalysis of data from 51 epidemiological studies of 52 705 women with breast cancer and 108 411 women without breast cancer. The Lancet. 350. 9084. 1997. 1047–1059. 0140-6736. 10.1016/S0140-6736(97)08233-0. 54389746. free.
3. Type and timing of menopausal hormone therapy and breast cancer risk: individual participant meta-analysis of the worldwide epidemiological evidence . Lancet . 394 . 10204 . 1159–1168 . September 2019 . 31474332 . 6891893 . 10.1016/S0140-6736(19)31709-X . Collaborative Group on Hormonal Factors in Breast Cancer .
4. Menarche, menopause, and breast cancer risk: individual participant meta-analysis, including 118 964 women with breast cancer from 117 epidemiological studies. The Lancet Oncology. 13. 11. 2012. 1141–1151. 1470-2045. 10.1016/S1470-2045(12)70425-4. 3488186 . 23084519. free. Collaborative Group on Hormonal Factors in Breast Cancer .