| Colfontaine | |
| Picture-Legend: | Colfontaine Town Hall |
| Map: | Colfontaine Hainaut Belgium Map.svg |
| Map-Legend: | Location of Colfontaine in Hainaut |
| Arms: | CommunesBelgique-Colfontaine.svg |
| Flag: | Colfontaine Belgium.svg |
| Arrondissement: | Mons |
| Nis: | 53082 |
| Mayor: | Luciano D'Antonio |
| Majority: | PS |
| Postal-Codes: | 7340 |
| Telephone-Area: | 065 |
| Web: | www.colfontaine.be |
| Coordinates: | 50.4167°N 54°W |
Colfontaine (pronounced as /fr/; wa|Colfontinne; pcd|Colfontinne) is a municipality of Wallonia located in the province of Hainaut, Belgium.
On 1 January 2006, the municipality had 20,021 inhabitants. The total area is 13.62 km2, giving a population density of 1,470 inhabitants per km2.
The municipality consists of the following districts: Pâturages, Warquignies, Wasmes (town centre; it includes the village of Petit Wasmes).