Cocksfoot mottle virus explained

Cocksfoot mottle virus (CfMV) is a pathogenic plant virus belonging to the genus Sobemovirus. The virus appears in southern and central England. It is transmitted by beetles Lema melanopa and Lema lichenis and is common in crops of cocksfoot and cocksfoot/legume mixtures.^[1]

Molecular biology

CfMV's P1 protein, required for infection, has been found to interfere with RNAi pathways in plants species such as Nicotiana benthamiana and Nicotiana tabacum.^[2]

The polyprotein coat of CfMV is made up of two proteins, encoded by overlapping open reading frames (2a and 2b) which are transcribed through a ribosomal frameshift mechanism.^[3] This mechanism is reliant upon a small stem-loop structure and a 'slippery' repeat sequence which allows programmed ribosomal frameshifting.^[4]

External links

• ICTVdB - The Universal Virus Database: Cocksfoot mottle virus
• Family Groups - The Baltimore Method

Notes and References

1. Web site: Show DPV and Refs in Frame.
2. Cecilia Sarmiento . Eva Gomez . Merike Meier . Tony A Kavanagh . Erkki Truve . amp . Cocksfoot mottle virus P1 suppresses RNA silencing in Nicotiana benthamiana and Nicotiana tabacum . . 123 . 1 . 95–99 . January 2007 . 10.1016/j.virusres.2006.07.013 . 16971015.
3. Mäkinen K, Mäkeläinen K, Arshava N . Characterization of VPg and the polyprotein processing of cocksfoot mottle virus (genus Sobemovirus) . J. Gen. Virol. . 81 . Pt 11 . 2783–9 . November 2000 . 11038392 . 10.1099/0022-1317-81-11-2783 . 28 July 2020 . etal . free .
4. Tamm T, Suurväli J, Lucchesi J, Olspert A, Truve E . Stem-loop structure of Cocksfoot mottle virus RNA is indispensable for programmed -1 ribosomal frameshifting . Virus Res. . 146 . 1–2 . 73–80 . December 2009 . 19748532 . 10.1016/j.virusres.2009.09.002 . 7114514 .