Clovamide Explained

Clovamide is a chemical compound found in cacao.[1] [2] It has only been found in small amounts.[3] It is also found in Trifolium pratense (red clover).[4]

Clovamide can exist as either the cis- or trans- isomer.

In isolated neuroblastoma cells, clovamide has in vitro neuroprotective effects.[5]

See also

Notes and References

  1. 10.1021/jf970575o. Antioxidative Polyphenols Isolated from Theobromacacao. 1998. Sanbongi. Chiaki. Osakabe. Naomi. Natsume. Midori. Takizawa. Toshio. Gomi. Shuichi. Osawa. Toshihiko. Journal of Agricultural and Food Chemistry. 46. 2. 454–457. 10554262.
  2. 10.1016/j.foodchem.2007.07.009. Roasting impact on the contents of clovamide (N-caffeoyl-L-DOPA) and the antioxidant activity of cocoa beans (Theobroma cacao L.). 2008. Arlorio. Marco. Locatelli. Monica. Travaglia. Fabiano. Coïsson. Jean-Daniel. Grosso. Erika Del. Minassi. Alberto. Appendino. Giovanni. Martelli. Aldo. Food Chemistry. 106. 3. 967–975.
  3. Book: Caballero . B. . Finglas . P. . Toldrรก . F. . Encyclopedia of Food and Health . Elsevier Science . 2015 . 978-0-12-384953-3 . 189.
  4. Induction of clovamide by jasmonic acid in red clover. Tebayashi S, Ishihara A, Tsuda M and Iwamura H, Phytochemistry, 2000 Jun, 54(4), pages 387-392,
  5. 2737666. 2009. Fallarini. S.. Clovamide and rosmarinic acid induce neuroprotective effects in in vitro models of neuronal death. British Journal of Pharmacology. 157. 6. 1072–1084. Miglio. G.. Paoletti. T.. Minassi. A.. Amoruso. A.. Bardelli. C.. Brunelleschi. S.. Lombardi. G.. 19466982. 10.1111/j.1476-5381.2009.00213.x.

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