Clotizolam Explained

Clotizolam (Ro11-1465) is a thienotriazolodiazepine derivative first invented in the 1970s, which in more recent years has been sold as a designer drug. As with other related thienotriazolodiazepines, it produces sedative, anxiolytic, anticonvulsant and muscle relaxant effects,^[1] and also acts as an inhibitor of platelet-activating factor (PAF).^[2]

See also

• Brotizolam
• Etizolam
• Flubrotizolam
• Fluclotizolam
• Deschloroclotizolam
• Ro09-9212
• Triazolam

Notes and References

1. Thienotriazolodiazepine derivatives . Hellerbach J, Zeller P, Binder D, Hromatka O . Hoffmann La Roche Inc . 22 May 1979 . US . 4155913 . . .
2. Tahara T, Mikashima H, Terasawa M, Maruyama Y . PAF antagonistic activity of some thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepines . Chemical & Pharmaceutical Bulletin . 35 . 5 . 2119–21 . May 1987 . 3664818 . 10.1248/cpb.35.2119 . 27564672 . free .