Clostridium autoethanogenum explained

Clostridium autoethanogenum is an anaerobic bacterium that produces ethanol from carbon monoxide, in so-called syngas fermentation, being one of the few known microorganisms to do so. It is gram-positive, spore-forming, rod-like, motile, and was first isolated from rabbit feces. Its type strain is strain JA1-1.^[1] Its genome has been sequenced ^[2] and the genes required for utilising carbon monoxide as a sole carbon and energy source have been determined.^[3]

Uses

This species is the key to the technology developed by Lanzatech to create ethanol from waste carbon monoxide gas of factory emissions.

Further reading

• Guo. Ying. Xu. Jingliang. Zhang. Yu. Xu. Huijuan. Yuan. Zhenhong. Li. Dong. Medium optimization for ethanol production with Clostridium autoethanogenum with carbon monoxide as sole carbon source. Bioresource Technology. 101. 22. 2010. 8784–8789. 0960-8524. 10.1016/j.biortech.2010.06.072. 20619639. *Cotter. Jacqueline L.. Chinn. Mari S.. Grunden. Amy M.. Ethanol and acetate production by Clostridium ljungdahlii and Clostridium autoethanogenum using resting cells. Bioprocess and Biosystems Engineering. 32. 3. 2008. 369–380. 1615-7591. 10.1007/s00449-008-0256-y. 18726618. 3041917.
• Liew. Fungmin Eric. Nogle. Robert. Carbon-negative production of acetone and isopropanol by gas fermentation at industrial pilot scale. Nature Biotechnology. 2022.

External links

• • LPSN

Notes and References

1. Abrini. Jamal. Naveau. Henry. Nyns. Edmond-Jacques. Clostridium autoethanogenum, sp. nov., an anaerobic bacterium that produces ethanol from carbon monoxide. Archives of Microbiology. 161. 4. 1994. 345–351. 0302-8933. 10.1007/BF00303591. 206774310.
2. Bruno-Barcena. J. M.. Chinn. M. S.. Grunden. A. M.. Genome Sequence of the Autotrophic Acetogen Clostridium autoethanogenum JA1-1 Strain DSM 10061, a Producer of Ethanol from Carbon Monoxide. Genome Announcements. 1. 4. 2013. e00628-13–e00628-13. 2169-8287. 10.1128/genomeA.00628-13. 23950130. 3744686.
3. Woods . Craig . Humphreys . Christopher M. . Tomi-Andrino . Claudio . Henstra . Anne M. . Köpke . Michael . Simpson . Sean D. . Winzer . Klaus . Minton . Nigel P. . 2022-04-12 . Nojiri . Hideaki . Required Gene Set for Autotrophic Growth of Clostridium autoethanogenum . Applied and Environmental Microbiology . en . 88 . 7 . e02479–21 . 10.1128/aem.02479-21 . 0099-2240 . 9004356 . 35285680.