| Cliff Speegle | |
| Birth Date: | 5 November 1917 |
| Birth Place: | Roosevelt, Oklahoma, U.S. |
| Death Place: | Dallas, Texas, U.S. |
| Player Years1: | 1938–1940 |
| Player Team1: | Oklahoma |
| Player Years2: | 1945 |
| Player Team2: | Chicago Cardinals |
| Player Positions: | Center |
| Coach Years1: | 1952–1953 |
| Coach Team1: | Colgate (line) |
| Coach Years2: | 1954 |
| Coach Team2: | Edmonton Eskimos (line) |
| Coach Years3: | 1955–1962 |
| Coach Team3: | Oklahoma A&M/State |
| Coach Years4: | 1963–1964 |
| Coach Team4: | Toronto Argonauts (assistant) |
| Coach Years5: | 1965–1966 |
| Coach Team5: | Texas Western (assistant) |
| Admin Years1: | 1973–1982 |
| Admin Team1: | SWC (commissioner) |
| Overall Record: | 36–42–3 |
| Bowl Record: | 1–0 |
| Awards: | |
Clifton M. Speegle (November 4, 1917 – September 5, 1994) was an American football player, coach, and college athletics administrator. He served as the head football coach at Oklahoma State University–Stillwater from 1955 to 1962, compiling a record of 36–42–3. During his tenure, Oklahoma State was 0–8 in the Bedlam Series, their rivalry game against the Oklahoma Sooners. Speegle was fired in 1962. He played college football at the University of Oklahoma from 1938 to 1940.