| Clarence Wetzel | |
| Birth Date: | February 24, 1899 |
| Death Place: | Salem, Ohio, United States |
| State House: | Ohio |
| State: | Ohio |
| District: | 34th |
| Term: | January 3, 1949-December 31, 1970 |
| Preceded: | District Created |
| Succeeded: | John Wargo |
| Party: | Republican |
Clarence Wetzel (February 24, 1899 - June 1972) was a member of the Ohio House of Representatives.
Hailing from Columbiana, Wetzel was a longtime politician, notably as a long term state representative.[1] He ran for Ohio's 18th congressional district in 1952. He was defeated in 1970 by John Wargo.