Citrobacter sedlakii explained

Citrobacter sedlakii is a species of Gram-negative bacteria.^[1] It has been described as causing human disease, but is generally found as a non-pathogenic organism in human stools.

History

Citrobacter sedlakii was originally isolated from human stool and wounds as strains of Citrobacter freundii.^[1] However, in 1993 six strains of C. freundii were identified as a separate species based on DNA hybridization, and were named C. sedlakii to honor Czech microbiologist Jiri Sedlak.^[1]

Description

Citrobacter sedlakii is a rod-shaped gram-negative bacterium. It can be distinguished from other Citrobacter species by its ability to produce indole, arginine dihydrolase activity, and ornithine decarboxylase activity.^[1]

Role in disease

Citrobacter sedlakii was originally isolated from human stool and wounds and was suggested to be pathogenic in humans.^[1] While some reports have described C. sedlakii as causing illness in humans, it is frequently found in stool and is not thought to be pathogenic in most cases.^[2] C. sedlakii can express the O157 antigen which is commonly found on pathogenic E. coli, however this does not cause disease.^[3]

External links

• • LPSN
• Type strain of Citrobacter sedlakii at BacDive - the Bacterial Diversity Metadatabase

Notes and References

1. Brenner. D. J.. Grimont. P. A. D.. Steigerwalt. A. G.. Fanning. G. R.. Ageron. E.. Riddle. C. F.. Classification of Citrobacteria by DNA Hybridization: Designation of Citrobacter farmeri sp. nov., Citrobacter youngae sp. nov., Citrobacter braakii sp. nov., Citrobacter werkmanii sp. nov., Citrobacter sedlakii sp. nov., and Three Unnamed Citrobacter Genomospecies. International Journal of Systematic Bacteriology. 43. 4. 1993. 645–658. 0020-7713. 10.1099/00207713-43-4-645. 8240948. free.
2. Citrobacter sedlakii Meningitis and Brain Abscess in a Premature Infant . James Dyer . Karen C. Hayani . William M. Janda . Paul C. Schreckenberger . 10 July 1997 . Journal of Clinical Microbiology . American Society for Microbiology . 35 . 10 . 2686–2688 . 10.1128/JCM.35.10.2686-2688.1997 . https://web.archive.org/web/20161220040027/http://jcm.asm.org/content/35/10/2686.full.pdf . 20 December 2016 . live . 9316937 . 230040 .
3. Isolation of a Nonpathogenic Strain of Citrobacter sedlakii Which Expresses Escherichia coli O157 Antigen . C.H. Park . E.A. Martin . E.L. White . Journal of Clinical Microbiology . American Society for Microbiology . 27 January 1998 . 36 . 5 . 1408–1409 . 10.1128/JCM.36.5.1408-1409.1998 . 104838 . 9574715 .