Cinchonine Explained
Cinchonine is an alkaloid found in Cinchona officinalis. It is used in asymmetric synthesis in organic chemistry. It is a stereoisomer and pseudo-enantiomer of cinchonidine.
It is structurally similar to quinine, an antimalarial drug.
It is a GLP-1 receptor agonist and therefore has potential as a possible treatment for obesity, type 2 diabetes, and non-alcoholic fatty liver disease.[1]
References
- Xue . Huan . Xing . Hao-Jie . Wang . Bin . Fu . Chao . Zhang . Yu-Shan . Qiao . Xi . Guo . Chao . Zhang . Xiao-Li . Hu . Bin . Zhao . Xin . Deng . Li-Jiao . Zhu . Xiao-Chan . Zhang . Yi . Liu . Yun-Feng . Cinchonine, a Potential Oral Small-Molecule Glucagon-Like Peptide-1 Receptor Agonist, Lowers Blood Glucose and Ameliorates Non-Alcoholic Steatohepatitis . Drug Design, Development and Therapy . 11 May 2023 . 17 . 1417–1432 . 10.2147/DDDT.S404055 . English. free . 10184894 .