Cinchonain-Ib Explained

Cinchonain-Ib is a flavonolignan found in the bark of Trichilia catigua used as catuaba.^[1] A 2009 study revealed that Cinchonian-Ib derived from boiled Eriobotrya japonica leaves has a glucose-lowering effect in rats, and could possibly be used to manage diabetes mellitus in humans.^[2]

Notes and References

1. Beltrame, F. L. . Filho, E. R. . Barros, F. A. P. . Cortez, D. A. G. . Casset, Q. B. . A validated higher-performance liquid chromatography method for quantification of cinchonain Ib in bark and phytopharmaceuticals of Trichilia catigua used as Catuaba . Journal of Chromatography A . 2006 . 1119 . 1–2 . 257–263 . 10.1016/j.chroma.2005.10.050 . 16360665 .
2. Qa’dan . Fadi . Verspohl . Eugen. J. . Nahrstedt . Adolf . Petereit . Frank . Matalka . Khalid Z. . Cinchonain Ib isolated from Eriobotrya japonica induces insulin secretion in vitro and in vivo . Journal of Ethnopharmacology . 15 July 2009 . 124 . 2 . 224–227 . 10.1016/j.jep.2009.04.023 . 19397981 . 19 October 2022 . en . 0378-8741.