Chromium(III) nicotinate explained

Iupac Name:	Chromium(3+) tri(pyridine-3-carboxylate)
Cas Number:	64452-96-6
Unii:	A150AY412V
Atc Prefix:	none
Pubchem:	56843898
Chemspiderid:	8085563
Synonyms:	Chromium trinicotinate
C:	18
H:	12
Cr:	1
N:	3
O:	6
Smiles:	[Cr+3].[O-]C(=O)c1cccnc1.[O-]C(=O)c1cccnc1.[O-]C(=O)c1cccnc1
Stdinchi:	1S/3C6H5NO2.Cr/c3*8-6(9)5-2-1-3-7-4-5;/h3*1-4H,(H,8,9);/q;;;+3/p-3
Stdinchikey:	MSPQQAUTCRWLGR-UHFFFAOYSA-K

Chromium(III) nicotinate is an ionic substance used for chromium supplementation in some nutritional products, where it is also referred to as chromium polynicotinate. It appears in products that are referred to as a medical food used for nutritional support for conditions associated with diabetes mellitus type 2. The product is also known as "niacin-bound chromium".^[1]

Chemistry

Chromium(III) nicotinate contains three nicotinic acid units per chromium ion; that is, it is the trinicotinate of chromium(III). The substance that is used in supplements and called "chromium polynicotinate" is said to be a mixture of the trinicotinate and the dinicotinate, with the former dominating.^[2]

See also

• Chromium(III) picolinate

Notes and References

1. Preuss HG, Bagchi D, Bagchi M, Rao CV, Dey DK, Satyanarayana S . Effects of a natural extract of (-)-hydroxycitric acid (HCA-SX) and a combination of HCA-SX plus niacin-bound chromium and Gymnema sylvestre extract on weight loss . Diabetes, Obesity & Metabolism . 6 . 3 . 171–80 . May 2004 . 15056124 . 10.1111/j.1462-8902.2004.00328.x . 36237508 .
2. European Food Safety Authority (EFSA) . Mixture of chromium di- and tri-nicotinate as a source of chromium added for nutritional purposes in food supplements and in foods for particular nutritional uses. The EFSA Journal. 2008. 887. 1–24. 10.2903/j.efsa.2008.887. free.