Christopher Chetsanga Explained

Christopher J Chetsanga
Birth Date:22 August 1935
Birth Place:Murehwa, Rhodesia (now Zimbabwe)
Nationality:Zimbabwean
Field:Biochemistry
Molecular Biology
Alma Mater:University of California
Pepperdine University
University of Toronto
Known For:Discovery of two enzymes involved in DNA repair
Academic administration

Christopher J. Chetsanga (born 1935 in Murehwa, Rhodesia) is a prominent Zimbabwean scientist who is a member of the African Academy of Sciences and The World Academy of Sciences.[1] [2] He discovered two enzymes involved in DNA repair. He has also held various academic administrative posts like Vice-Chancellor, Director and Dean.

Biography

Chetsanga was born in Murewa, Zimbabwe on 22 August 1935,[3] and was baptised in 1948. In his youth, he was educated at Nhowe Mission, and went on to study at University of California, Berkeley where he received his BSc in 1965. Chetsanga also studied for a period at Pepperdine University.[4] In 1969, he received his MSc and PhD in biochemistry and molecular biology from University of Toronto before becoming a post doctoral fellow at Harvard University between 1969 and 1972. Between 1972 and 1983 he became a professor at the University of Michigan, then in 1983 he left to become the senior lecturer in Biochemistry for University of Zimbabwe.[5] In 1990, President Robert Mugabe awarded him President’s Award for Distinguished Contribution to Science and Technology.[6] [7] Has also awarded the Order of the Star of Zimbabwe.[8] He is presently the vice chancellor at Zimbabwe Ezekiel Guti University.[9]

In 2004, when the Zimbabwe Academy of Sciences was formed, Chetsanga was appointed the first president of the academy.[10] Chetsanga advocated the use of genetically modified food sources as a possible solution for food shortages in Africa in 2020.[11]

Scientific Achievements

Chetsanga has discovered two enzymes involved in the repair of damaged DNA: firstly, formamidopyrimidine DNA glycosylase, which removes damaged 7-methylguanine from DNA (1979),[12] and secondly, purine imidazole-ring cyclase, which re-closes imidazole rings of guanine and adenine damaged by x-irradiation (1985).[13]

According to Chetsanga, his research focus in his scientific career has been on DNA and RNA structural and functional details as they relate to cellular metabolism and disease development.[14]

External links

Notes and References

  1. AAS. "Chetsanga, J. Christophe, Prof.", Fellow of AAS since 1986; Biochemistry and Molecular Biology, Nairobi, unknown. Retrieved on 28 August 2014.
  2. Web site: Christopher Chetsanga - Pepperdine's Outstanding Alumni Abroad Pepperdine University . 2022-10-03 . www.pepperdine.edu.
  3. Web site: CHETSANGA Christopher J. . TWAS . The World Academy of Science . 19 July 2020.
  4. Book: David Mubvumbi . Paradzayi . Christianity And Traditional Religions Of Zimbabwe : Contrasts And Similarities. . 2016 . Westbow Press . 9781512745108 . 19 July 2020.
  5. News: Prof. Christopher James Chetsanga . 19 July 2020. University of Zimbabwe.
  6. News: EAI International Conference for Research, Innovation and Development for Africa . 19 July 2020 . EAI . June 2017.
  7. Web site: Chetsanga Christopher . African Academy of Sciences . 19 July 2020.
  8. Web site: Ziana . New . 2021-08-09 . Zimbabwe awards civilian heroes - New Ziana . 2022-10-03 . en-GB.
  9. Web site: Zimbabwe Ezekiel Guti University - Home. 2021-06-02. www.zegu.ac.zw.
  10. News: OWSD Zimbabwe National Chapter is Launched . 19 July 2020 . Organization for women in science for the developing world . 20 November 2018.
  11. News: GMB to import GMO Maize . 19 July 2020 . NewsdzeZimbabwe . 23 April 2020.
  12. Chetsanga, C.J. . Lindahl, T. . 1979 . Release of 7-methylguanine residues whose imidazole rings have been opened from damaged DNA by a DNA glycosylase from Escherichia coli . Nucleic Acids Res . 6 . 11 . 3673–84 . 10.1093/nar/6.11.3673 . 386277 . 327965 .
  13. Chetsanga, C.J. . Grigorian, C. . 1985 . In situ enzymatic reclosure of opened imidazole rings of purines in DNA damaged by gamma-irradiation . Proceedings of the National Academy of Sciences of the United States of America . 82 . 3 . 633–637 . 10.1073/pnas.82.3.633 . 3856219 . 397099 . 25324. 1985PNAS...82..633C . free .
  14. Web site: Christopher J. Chetsanga . Pepperdine . 19 July 2020.