Christian Karsten Hansen Explained

Christian Karsten Hansen (born 18 August 1966) is a Danish biotechnology entrepreneur, investor and inventor, with work in new drugs, molecular biology and biochemistry.

Personal background

Originally from Copenhagen (Denmark), he spent his childhood in Antwerp, Belgium and Caracas, Venezuela before completing high school at Sorø Academy in 1984. Following graduation as MSc chemical engineering from the Technical University of Denmark in 1989,[1] PhD work in molecular biology and biochemistry was conducted at the Pasteur Institute,[2] [3] [4] France and the University of Salamanca,[5] Spain. He also completed an MBA from the Edinburgh Business School, Scotland.[6]

Professional background

Hansen held positions as senior scientist and director of intellectual property management at Novo Nordisk 1992–1999, and was a member of Enzyme Research Management.[6] He co-founded one of the early Danish biotechnology companies, Profound Pharma,[7] [8] in 1999, with Jan Møller Mikkelsen,[9] and remained co-CEO thereof until its acquisition by Maxygen in 2000.[10] In 2001, he co-founded the investment firm Nordic Biotech Advisors,[1] [11] subsequently renamed NB Capital.[12] [13] [14] [15] [16] [17] Also in 2001, he founded C Hansen Invest.

Since 2001, Hansen has co-founded and/or been a board member of numerous privately held and listed biotechnology companies including Osteologix,[18] [19] Nuevolution,[15] [20] Curalogic,[6] Forward Pharma,[21] Rose Pharma,[22] Poalis,[15] Aditech Pharma, Veloxis Pharmaceuticals,[23] H Pharmaceuticals, Isar Pharma,[24] and ParaTech.[25]

Patents

Hansen has filed numerous patent applications in the fields of genetics of bacteria, cellulases and other enzymes, osteoporosis, and protein engineering and uses of biopharmaceuticals. He is named as inventor of issued European patents 510091,[26] 1250154,[27] 1425304,[28] 1534305,[29] 1622629,[30] 1622630,[31] 1732575,[32] 1745791[33] 2266584[34] and 2266585,[35] and US patents 5,843,720,[36] 5,916,796,[37] 6,066,473,[38] 6,555,660,[39] 6,646,110,[40] 6,831,158,[41] 7,230,081,[42] 7,232,562,[43] 7,504,237,[44] 7,550,565,[45] 7,550,566,[46] 7,595,342,[47] 7,696,153[48] and 8,541,471.[49]

Various compounds from these companies and patents are in mid and late stages of clinical development.[50] [51]

Notes and References

  1. Web site: Festglad venturekapitalist – Diverse . 10 November 2005 . Business.dk . 10 November 2011.
  2. Hansen . C K . Diderichsen . B . Jørgensen . P L . celA from Bacillus lautus PL236 encodes a novel cellulose-binding endo-beta-1,4-glucanase . Journal of Bacteriology . June 1992 . 174 . 11 . 3522–3531 . 10.1128/jb.174.11.3522-3531.1992 . 1592807 . 206037 .
  3. Gene : In vivo genetic engineering: homologous recombination as a tool for plasmid construction . 10.1016/0378-1119(90)90338-R . 2265757 . 96 . 1 . 1990 . Gene . 37–41 . Jørgensen Per L., Hansen Christian K., Poulsen Gitte B., Diderichsen Børge.
  4. Gene : Multiple endo-β-1,4-glucanase-encoding genes from Bacillus lactus PL236 and characterization of the celB gene . 10.1016/0378-1119(90)90135-E . 2227426 . 93 . 1 . 1990 . Gene . 55–60 . Jørgensen Per L., Hansen Christian K..
  5. FEBS Letters : Fibronectin type III-like sequences and a new domain type in prokaryotic depolymerases with insoluble substrates . FEBS Letters . 305 . 2 . 91–96 . 10.1016/0014-5793(92)80871-D. 1618347 . 1992 . Hansen . Christian K. . 33177292 . free .
  6. Web site: Archived copy . 17 January 2011 . 19 July 2011 . https://web.archive.org/web/20110719122632/http://www.euroinvestor.dk/pdf/cse/140531-0.pdf . dead .
  7. Web site: Rose Pharma – Board . Gastrotechpharma.com . 10 November 2011 . dead . https://web.archive.org/web/20081121063546/http://www.gastrotechpharma.com/board.html . 21 November 2008 .
  8. Web site: Speed, aggression, surprise! . Mva.org . 10 November 2011 . dead . https://web.archive.org/web/20110728090138/http://www.mva.org/content/us/the_region/start-up_a_company/patent_strategy/get_inspired . 28 July 2011 .
  9. Web site: Dansk bioteks Lance Armstrong – Navne . 3 August 2010 . Business.dk . 10 November 2011.
  10. Web site: Maxygen Reports 2000 Third quarter Financial Results. – Free Online Library . Thefreelibrary.com . 10 November 2011.
  11. Web site: Medicon Valley Patent Guide . 2011-01-17 . dead . https://web.archive.org/web/20110727104526/http://www.mva.org/media%281947%2C1033%29/Medicon_Valley_Patent_Guide.pdf . 27 July 2011 .
  12. Web site: NB Capital . NB Capital . 10 November 2011.
  13. Web site: Vækstfonden – Portefølje . Vf.dk . 10 November 2011.
  14. Web site: European Biotechnology News :: Nordic biotech gets Euro41.5m fund . https://web.archive.org/web/20110720161125/http://www.eurobiotechnews.eu/northern-europe/denmark/articledetail/?tx_ttnews%5Bpointer%5D=17&tx_ttnews%5Btt_news%5D=3872&tx_ttnews%5BbackPid%5D=31&cHash=6dd205a7d5 . dead . 20 July 2011 . Eurobiotechnews.eu . 10 November 2011 .
  15. Web site: Danish venture capital company Nordic Biotech raises second biotech venture fund (in English) . Mva.org . 10 November 2011 . dead . https://web.archive.org/web/20110911172330/http://www.mva.org/composite-62.htm . 11 September 2011 .
  16. Web site: Discover Relevant Business Information. venturebeatprofiles.com. 17 January 2011. https://archive.today/20120718190051/http://venturebeatprofiles.com/person/profile/christian-hansen. 18 July 2012. dead.
  17. Web site: Christian Hansen PhD . NB Capital ApS: Private Company Information – BusinessWeek . Investing.businessweek.com . 10 November 2011.
  18. Web site: 2005 Archives . Osteologix . 29 November 2004 . 10 November 2011.
  19. Web site: Archived copy . 17 January 2011 . 17 March 2012 . https://web.archive.org/web/20120317070348/http://www.osteologix.com/media/10q_2009_q2.pdf . dead .
  20. Web site: Biotech companies in Medicon Valley popular among investors – Invest in Denmark . Investindk.com . 30 October 2007 . 10 November 2011.
  21. Web site: Christian Hanse . Forward-pharma.com . 10 November 2011 . dead . https://web.archive.org/web/20110711021134/http://www.forward-pharma.com/test/ChristianHanse.htm . 11 July 2011 .
  22. Web site: Rose Pharma . 2011-01-14 . dead . https://web.archive.org/web/20110118063851/http://www.rosepharma.com/ . 18 January 2011 .
  23. Web site: Medicon Valley Financing Guide . 2011-01-17 . dead . https://web.archive.org/web/20110627102816/http://www.mva.org/media%281946%2C1033%29/Financing_Guide_2004.pdf . 27 June 2011 .
  24. Web site: Isar Pharma K/S: News Release . Marketwire.com . 10 November 2011.
  25. Web site: Board Members ParaTech. para-tech.dk. 2017-07-28. https://web.archive.org/web/20170728120159/http://para-tech.dk/about-us/board-members/. 28 July 2017. dead.
  26. Web site: Espacenet – Bibliographic data.
  27. Web site: espacenet – Bibliographic data . V3.espacenet.com . 23 October 2002 . 10 November 2011.
  28. Web site: espacenet – Bibliographic data . V3.espacenet.com . 9 June 2004 . 10 November 2011.
  29. Web site: espacenet – Original document . V3.espacenet.com . 10 November 2011.
  30. Web site: Espacenet – Bibliographic data.
  31. Web site: Espacenet – Bibliographic data.
  32. Web site: espacenet – Bibliographic data . V3.espacenet.com . 20 December 2006 . 10 November 2011.
  33. Web site: Espacenet – Bibliographic data.
  34. Web site: Espacenet – Bibliographic data.
  35. Web site: Espacenet – Bibliographic data.
  36. Web site: Introduction of DNA into bacillus strains by conjugation – US Patent 5843720 Description . Patentstorm.us . 10 November 2011 . dead . https://web.archive.org/web/20121011124736/http://www.patentstorm.us/patents/5843720/description.html . 11 October 2012 .
  37. Web site: Enzyme exhibiting cellulase activity – US Patent 5916796 Full Text . Patentstorm.us . 10 November 2011 . dead . https://web.archive.org/web/20121011124829/http://www.patentstorm.us/patents/5916796/fulltext.html . 11 October 2012 .
  38. Web site: Introduction of DNA into bacillus strains by conjugation – US Patent 6066473 Description . Patentstorm.us . 10 November 2011 . dead . https://web.archive.org/web/20121011124859/http://www.patentstorm.us/patents/6066473/description.html . 11 October 2012 .
  39. Web site: G-CSF conjugates – US Patent 6555660 Full Text . Patentstorm.us . 10 November 2011 . dead . https://web.archive.org/web/20121011124923/http://www.patentstorm.us/patents/6555660/fulltext.html . 11 October 2012 .
  40. Web site: G-CSF polypeptides and conjugates – US Patent 6646110 Full Text . Patentstorm.us . 10 November 2011 . dead . https://web.archive.org/web/20121011124943/http://www.patentstorm.us/patents/6646110/fulltext.html . 11 October 2012 .
  41. Web site: G-CSF conjugates – US Patent 6831158 Full Text . Patentstorm.us . 10 November 2011 . dead . https://web.archive.org/web/20121011125012/http://www.patentstorm.us/patents/6831158/fulltext.html . 11 October 2012 .
  42. Web site: Interferon gamma conjugates – US Patent 7230081 Full Text . Patentstorm.us . 10 November 2011 . dead . https://web.archive.org/web/20121011161953/http://www.patentstorm.us/patents/7230081/fulltext.html . 11 October 2012 .
  43. Web site: E38N interferon gamma polypeptide variants – US Patent 7232562 Full Text . Patentstorm.us . 10 November 2011 . dead . https://web.archive.org/web/20121011162014/http://www.patentstorm.us/patents/7232562/fulltext.html . 11 October 2012 .
  44. Web site: Polynucleotides encoding interferon gamma polypeptides – US Patent 7504237 Full Text . Patentstorm.us . 10 November 2011 . dead . https://web.archive.org/web/20121011162036/http://www.patentstorm.us/patents/7504237/fulltext.html . 11 October 2012 .
  45. Web site: G-CSF conjugates – US Patent 7550565 Full Text . Patentstorm.us . 10 November 2011 . dead . https://web.archive.org/web/20121011162102/http://www.patentstorm.us/patents/7550565/fulltext.html . 11 October 2012 .
  46. Web site: G-CSF conjugates – US Patent 7550566 Full Text . Patentstorm.us . 10 November 2011 . dead . https://web.archive.org/web/20121011162245/http://www.patentstorm.us/patents/7550566/fulltext.html . 11 October 2012 .
  47. Web site: Water-soluble strontium salts for use in treatment of cartilage and/or bone conditions – US Patent 7595342 Full Text . Patentstorm.us . 10 November 2011 . dead . https://web.archive.org/web/20121011162307/http://www.patentstorm.us/patents/7595342/fulltext.html . 11 October 2012 .
  48. Web site: G-CSF conjugates – US Patent 7696153 Full Text . Patentstorm.us . 10 November 2011 . dead . https://web.archive.org/web/20121011162342/http://www.patentstorm.us/patents/7696153/fulltext.html . 11 October 2012 .
  49. Web site: Water-soluble strontium salts for use in treatment of cartilage and/Or bone conditions - US Patent 8541471 Full Text . www.patentstorm.us . 6 June 2022 . https://archive.today/20130927073231/http://www.patentstorm.us/patents/8541471/fulltext.html . 27 September 2013 . dead.
  50. Web site: News . Osteologix . 30 March 2009 . 10 November 2011.
  51. Web site: Treatment of Neutropenia, G-CSF, Neutrophils, Chemotherapy, Protein Therapeutics, Pegylated, Clinical Trial, Neupogen, Neulasta, Blood, Bone Marrow, Breast cancer, Lung cancer, Lymphomas, Leukemias . Maxygen.com . 10 November 2011 . dead . https://web.archive.org/web/20111012060208/http://www.maxygen.com/products-mye.php . 12 October 2011 .

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